Genetic Engineering Will Change Everything Forever - CRISPR

  • Published on Aug 10, 2016
  • Designer babies, the end of diseases, genetically modified humans that never age. Outrageous things that used to be science fiction are suddenly becoming reality. The only thing we know for sure is that things will change irreversibly.
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    Thanks to Volker Henn, James Gurney and (prefers anonymity) for help with this video!
    Jeffrey Schneider, Konstantin Kaganovich, Tom Leiser, Archie Castillo, Russell Eishard, Ben Kershaw, Marius Stollen, Henry Bowman, Ben Johns, Bogdan Radu, Sam Toland, Pierre Thalamy, Christopher Morgan, Rocks Arent People, Ross Devereux, Pascal Michaud, Derek DuBreuil, Sofia Quintero, Robert Swiniarski, Merkt Kızılırmak, Michelle Rowley, Andy Dong, Saphir Patel, Harris Rotto, Thomas Huzij, Ryan James Burke, NTRX, Chaz Lewis, Amir Resali, The War on Stupid, John Pestana, Lucien Delbert, iaDRM, Jacob Edwards, Lauritz Klaus, Jason Hunt, Marcus : ), Taylor Lau, Rhett H Eisenberg, Mr.Z, Jeremy Dumet, Fatman13, Kasturi Raghavan, Kousora, Rich Sekmistrz, Mozart Peter, Gaby Germanos, Andreas Hertle, Alena Vlachova, Zdravko Šašek
    The best book we read about the topic: GMO Sapiens
    (affiliate link, we get a cut if buy the book!)

    - Good Overview by Wired:
    -timeline of computer development:
    - Selective breeding:
    - DNA:
    - Radiation research:
    - inserting DNA snippets into organisms:
    - First genetically modified animal:
    - First GM patent:
    - chemicals produced by GMOs:
    - Flavr Savr Tomato:
    - First Human Engineering:
    - glowing fish:
    - CRISPR:
    - HIV cut from cells and rats with CRISPR:
    - first human CRISPR trials fighting cancer:
    first human CRISPR trial approved by Chinese for August 2016:
    - genetic diseases:
    - pregnancies with Down Syndrome terminated:
    ( 1999 European study)
    - CRISPR and aging:
    Help us caption & translate this video!

Comments • 57 152

  • Kurzgesagt – In a Nutshell

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    • Bobby Kids
      Bobby Kids 5 days ago +1


    • lorenzo koa
      lorenzo koa 9 days ago

      I am down to live forever. I don't have no choice because I have little time. Just like that movie about time.🎥

    • FireDrage
      FireDrage 11 days ago

      Kurzgesagt - In a Nutshell With every good thing they come a darkside

    • FireDrage
      FireDrage 11 days ago

      Kurzgesagt - In a Nutshell never say never!!!

    • Señor Churrasko
      Señor Churrasko 13 days ago

      M.A. R nuclear bomb, fuking trump

  • W 0o
    W 0o 5 minutes ago

    I feel like I’m in a movie

  • Nana Kwaku Akrofi
    Nana Kwaku Akrofi 3 hours ago


  • MikasaScarlett
    MikasaScarlett 4 hours ago

    I want to go super sayin! 😢

  • MikasaScarlett
    MikasaScarlett 4 hours ago

    Damn, now I want to be born in that era. Preferably with some type of super power

  • John Oliver
    John Oliver 8 hours ago

    cant wait to finally become a Super Saiyan, my neighbors hate that i keep waking them up with my attempts.

  • Cary Page
    Cary Page 9 hours ago

    Well that's fun

  • HeyRay
    HeyRay 10 hours ago

    Welp, I'll be dead by then, nothing for me to worry about.

    MrNINTENDOJOE 10 hours ago

    so the wrath of Khan is coming

  • Ethan P
    Ethan P 11 hours ago

    11:51 I agree!

  • Bowen Wang
    Bowen Wang 13 hours ago

    If you end your own aging, they should make it a law to not be allowed to have any children.

  • UForce
    UForce 14 hours ago

    The latest Video on the German Channel!

  • Cezy Il vaso
    Cezy Il vaso 15 hours ago

    Why not?

  • Icarus
    Icarus 16 hours ago

    11:27 Elon musk wya

  • Michelle Mailloux
    Michelle Mailloux 17 hours ago

    Galatians 6:7-9"Be not deceived, God is not mocked. For what things a man shall sow, those also shall he reap. For he that soweth in his flesh, of the flesh also shall reap corruption. But he that soweth in the spirit, of the spirit shall reap life everlasting." This scientific discovery/pursuit is completely evil.

  • phuc an nguyen ngoc
    phuc an nguyen ngoc 20 hours ago

    I hope this will happen soon so I can have new super power

  • F.B.I
    F.B.I 21 hour ago

    "All we need is to convince a smart billionaire"
    Me: _ahem_
    Me: _*EEEEEEEEELLLLLOOOOOOOOOOOOOOOOOOOOOOONNNNNNNN*_!!!!!!!!!!!!!!!1!1!1!1!1!!!!!!!11!!!!!!!

  • playerisplaying
    playerisplaying 23 hours ago

    We cannot live 2000 years with modified dna cus we can't remember ths 200 years

  • playerisplaying
    playerisplaying 23 hours ago

    I don't want to cure all diseases cuz i eanna get a day in home when im sick

  • Polyester cloth
    Polyester cloth 23 hours ago

    Talking animals

  • PanzerIV
    PanzerIV Day ago

    People living much longer would be the worst thing ever in humanity, and would doom our planet which is already overpopulated big time. There's too much humans for the # of ressources it has so unless there would be a limit of 1-2 human per family, having humans who won't ******* die and spread like cancer, it's a plan to end humanity.

  • Sky
    Sky Day ago +1

    Imagine microsoft advertising this in future :


  • Adrian Brent
    Adrian Brent Day ago

    God is great

  • bun bun lps
    bun bun lps Day ago +1

    my mom says designer babys r bad bc God made use not sciencetess

  • Mihai Vasile
    Mihai Vasile Day ago

    Ya'all so concerned if you could, but don't stop to think if you should...

  • vvv
    vvv Day ago

    Instead of designer clothes you now have designer babies

  • Marco Ganahl
    Marco Ganahl Day ago

    Ok Amazing... Crispr Cas9 forget about the designer Babies the only interresting thing would be engineering of already living beeings... if even this is possible then it will gonna affect me otherwise it can only affect next Generations... change something in your genes you are uncomfy with while you are alive would be great... monitor it and correct until it is done right. Disease free and shaped as you wish only your own imagination limits it

  • Infullbloom Time

    Why are people so stuck on the superficial crap looking like this and tall like that ... this is a breakthrough in health how many people with cancer or blood diseases or bone and eye conditions etc going to be able to live normal healthy lives! This is beautiful

  • Joshua Kovacs
    Joshua Kovacs Day ago

    "Nothing is that far off with what we're talking about.", eh?
    Gimme a Gundam and make my son a new-type.

  • Heinrich_ Himmler


  • Heinrich_ Himmler


  • Millipede
    Millipede Day ago

    This kind of makes me uncomfortable as an Autistic person: Well, on one hand, a lot of great things can come from genetic engineering, there are things others would consider flaws that are actually great and make the person who they are, like Autism, if I wasn't born Autistic I doubt I'd be interested in biology or Zoology, as well as many other things, I certainly wouldn't be who I am today, so the thought of that slowly being eliminated through genetic engineering is a scary thought. The idea that someone was able to detect something like Autism in an unborn child and somehow remove it before the child is born would be messed up...
    Imagine if in the future they find a way to stop Autism from developing, imagine all the amazing people we'd end up never having, people who can see the world in unique ways that can make them geniuses and create and do amazing things.
    idk, I think it could be messed up for that reason.

  • judy
    judy Day ago

    so... basically, creative mod?

  • Nicholas Tang
    Nicholas Tang Day ago +1

    It has been 2 years now. Was crispr successful in curing lung cancer?

    • Ronit Thakur
      Ronit Thakur 7 minutes ago

      Nicholas Tang google it and please tell me

  • Le SpoderMan
    Le SpoderMan Day ago

    the hail hydra might be even immortal

  • shun shit
    shun shit Day ago

    aint this how divergent started

  • Omi Gaia
    Omi Gaia Day ago

    Girl in future : why you shoot inside?!
    Boy : That my Kamehameha.

  • SebgamingYT
    SebgamingYT 2 days ago

    Its a good technology that can change our own life its risky but this tech can may change people mortal to immortal

  • Yash Raj Arora
    Yash Raj Arora 2 days ago

    12:22 Mudblood ^_^ lmao

  • rubiks6
    rubiks6 2 days ago

    Kurzgesagt - Are you folks closely related to a fella named Adolph Hitler? Trying to create the _"master"_ race?
    You folks are insidious, evil.

  • Carnival14
    Carnival14 2 days ago +1

    Oooo shit, the furries are gunna have a field day with this....

  • Jade Everest
    Jade Everest 2 days ago

    I love how he uses terminating a pregnancy rather than exactly what it is, ripping a baby out from their only way of survival.

  • Mehrio Time
    Mehrio Time 2 days ago +1

    *makes Sans undertale with Genetic Engineering*
    Go,My Son,Give the world a bad time.

  • David Panyuan
    David Panyuan 2 days ago

    If we get rid of cancer that will excel the growth rate of the worlds population. I’m not sure that’s a good idea, don’t get me wrong cancer is evil but it will cause another problem in the long run

  • Sheisun
    Sheisun 2 days ago +1

    What I'm worried about is when designer babies become a thing, parents might still choose not to have a designer baby. Now imagine a world where 9 out of 10 people are designer babies with perfect hair, super attractive, can eat 10 Big Macs a day and never get fat, sprint faster than Sonic, have an IQ of 200 (I could keep going), we're left with 10% of people who are just average. Or at this point, below average. They have some cushin' for the pushin' because their metabolism isn't perfect, their hair starts to grey at 30, they're a C-B grade student,. Those people will definitely be selected against. If they're less attractive they'll have a hard time finding a partner, employers might not want to employ them because they're seen as lesser compared to everyone else, they have a hard time socialising, they're perceived as stupid by colleagues and classmates because they're not at intelligent. Imagine how awful of a life this person would have. At this point the parents would opt to have a designer baby because they would want to avoid that kind of future for their child, but here's where ethics comes in. They do it because everyone else does it, not because they want to. Its no longer a choice, its a must, and if they don't do it they're basically putting their child up for a lifetime of discrimination and exclusion.
    On the other hand, designer babies might become more and more popular over time, and eventually pretty much everyone will be having designer babies because it became the norm, so these "average" people won't even exist anymore and everyone will be perfect. Or "perfect". But when everyone becomes "perfect", then will we be human anymore. Our flaws and imperfections are partially what defines us a human. Perfect will become the average, and when that happens, what next? We strive for something even more perfect, and at this point its almost certain that we'll just edit out all the human parts of ourselves so much that none of us will be human anymore. An entire planet of genetically modified species. Homo geneticus. Everything is bad when its in excess, including genetic modification. I think that when gene editing does become your everyday norm, there will be laws to control this. For example there may be a limited number of traits that you can choose for your child to have, or there will be certain traits that will be outright banned from being edited.
    Its both scary and fascinating. We could eventually get to the point where we can eliminate horrendous diseases by just editing them out of our genome, which is amazing, but while doing so we could completely eradicate the human species and create something else by accident, which is terrifying.

    • John Cavanaugh
      John Cavanaugh Day ago

      Isnt this what already happens? We just dont get to choose who will be the haves and who will be the have nots. its just luck.

  • Logan Dailey
    Logan Dailey 2 days ago

    Would you be able to theoretically modify yourself if you were not modified as a baby? Or do you have to be in the womb?

    • ST-1170
      ST-1170 19 hours ago

      Adults could be modified by modifying stem cells.
      Modifying these cells would allow adolescents and adults to benefit from these amazing technologies

  • Feroz Ahmadi
    Feroz Ahmadi 2 days ago

    I strongly believe that one day humans and everything will live longer by genetics

  • Tobiasz Czarnota
    Tobiasz Czarnota 2 days ago

    What does this translate to?

  • martial arts,music and history

    One day we will create Monsters

  • Berkay Arslan
    Berkay Arslan 2 days ago

    So, if we perfectly realize this technology in all around the world; is it gonna be the designer of the new perfect world or the apocalypse of the nature and Earth by the human population?

  • Mtr Abr
    Mtr Abr 3 days ago

    Great video

  • Night King
    Night King 3 days ago

    Hail crisper

  • Warren Peace
    Warren Peace 3 days ago

    What a world we live in

  • omair pelex biologest !

    Noooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooo please noooooooooooooooooooooooooooòoooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooooo

  • They Call Me C4
    They Call Me C4 3 days ago

    im PRikE RiCk

  • Endersteler no
    Endersteler no 3 days ago

    So in a few years we can create the saiyin race with tails and we would name our planet Vegeta.

  • TeenWhoLovesTea
    TeenWhoLovesTea 3 days ago +1

    Tokyo Ghoul is reality.

  • Elekea
    Elekea 3 days ago

    actually in the topic of metabolism, the lower metabolism the longer the lifespan because of the decay you also mentioned. it's why turtles live so long and rats live for so short

    NSITF MCPE 3 days ago +1

    who's from Mrs Mo

  • Enclair
    Enclair 3 days ago

    My teacher wants us to study this topics

  • Sam Lee
    Sam Lee 3 days ago

    Is anyone generally scared after watching this video? Or is that just me ?

  • Rinas Nachy
    Rinas Nachy 3 days ago +1

    3:37 Rick and Morty

  • MachoManAlex YT
    MachoManAlex YT 3 days ago

    One solution to the over-population immortality problem would make it so that your reproductive organs are permanently disabled once you take the immortality drug.

  • GoldenDogs445
    GoldenDogs445 3 days ago

    hooooo boys welcome to the end of humanity. that door we just opened? it’s the end! there are going to be massive wars when america starts making perfect soldiers and colonizing planets not to mention the over population pollution and starving plus we don’t know the long terms effects

  • Daniel McManus
    Daniel McManus 3 days ago

    We need to form an army so that we can kill every one of these unnatural fuck bags they make. Go to fucking mars shitheads, do what you want. Leave earth to the humans. We actually appreciate what earth and nature has given us

  • Johann Schumacher
    Johann Schumacher 3 days ago

    Woah this is so awesome in what world we all live in! PS: you animations are so good and smooth!

  • Balıklı Dondurma
    Balıklı Dondurma 3 days ago

    3:50 is a reference to song right ?

  • Liquidblack
    Liquidblack 3 days ago

    im not religious but this is wrong. A wrong decision will manifest itself in a negative way, im not just talking about ethics and delusional mind constructs, but about reality. edit: everything can be cured allready by yourself, yaya now throw stones at me....

  • Chrys Tian
    Chrys Tian 3 days ago

    Basically Red Rising...sweet!

  • Rik Singha
    Rik Singha 3 days ago

    Genetic Modification gave my son autism

  • Bobby Sandhu
    Bobby Sandhu 3 days ago

    This is how humans go extinct when the designer generation comes around humans will be gone. Being human means being flawed

  • ZERO
    ZERO 3 days ago

    Anti vaxxers will still die :D

  • reee eee
    reee eee 3 days ago

    Well they made the first engineered kid in China who was born who can’t ever get hiv

    • ZERO
      ZERO 3 days ago

      Fake news. The baby might still get HIV because the genetic changes made were not thoroughly researched.

  • helperbot 2000
    helperbot 2000 3 days ago

    wow, this is great!

  • Vrnold
    Vrnold 3 days ago

    i can already see tv shows like "crispr my body" in the future lol

  • Mike Lisanke
    Mike Lisanke 3 days ago

    Thanks for trying to normalize GMO Humans... nice try... and BTW, did you hear that CRISPR had a set back in which they found it can also shotgun wide sections of the genome with unknown consequences. Ever hear, don't F' with Mother Nature :-p. Just saying... I expect humanity will continue to have its Drs. Frankenstein and like GMO crops those changes will creep (intended) into the wild with Only God knows what consequences. At least, you're not talking Gene Drive Humans yet... right? :-p

  • xi0o OnYoutube
    xi0o OnYoutube 4 days ago

    The only thing i want is to live long enough to see dinasaurs come bac to life... and much more lol.

  • Koopa Methusela
    Koopa Methusela 4 days ago

    I know this is an old video.... but.... at 2:49 healthy is spelled "healty". You're welcome.

  • NoobonInstagram
    NoobonInstagram 4 days ago

    I'm 93% deaf. Can I edit my DNA and fix that now?

  • Alireza Asadi
    Alireza Asadi 4 days ago

    even if they get the technology to make humans imortal or increase their age thry wouldn't do it! it will cause a lot more troubles

  • Rouge
    Rouge 4 days ago

    I want to be 12 forever

  • Jacob You
    Jacob You 4 days ago

    The genocide against children will be seen as an atrocity in the future. What is to stop people from killing off those with brown eyes or other seemingly arbitrary characteristics? How is this any different from the nazis sterilizing those with learning disabilities?

    • ZERO
      ZERO 3 days ago

      Americans started Eugenics when the sterilized 'dumb' women and black people.

  • Keithan Diep
    Keithan Diep 4 days ago

    CRISPR creator has a death sentance over his head. PRAY FOR CRISPR

  • Navi Kukreja
    Navi Kukreja 4 days ago

    If u think this is interesting read a book called Scythe. The premise is that humanity has solved all problems of disease and aging. Basically it’s impossible to die. But the population must be regulated so there are a group of people called scythes that do it. Really interesting book that explores this concept

  • Maxis Maximov
    Maxis Maximov 4 days ago

    5:33 Wait.... Why are you diggin inside Blixer's head WITH A FRICKIN SCALPEL?!?!!?!?

  • Maxis Maximov
    Maxis Maximov 4 days ago

    3:34 Wait a minute: Why Rick and Morty are here? I thought Rick was doing some crazy stuff on other planets

  • Maxis Maximov
    Maxis Maximov 4 days ago

    2:18 Power-Up Mushroom! Yay!

  • Maxis Maximov
    Maxis Maximov 4 days ago

    1:41 The cactus turned into Mickey's head, and strawberries turned into Phirana Plants from -Mario- *LUIGI* games

  • Andy Lao
    Andy Lao 4 days ago

    Please beat cancer so I can eat hella smoked meats

  • Andy Lao
    Andy Lao 4 days ago

    There once was a genie with a ten foot weenie who went to the lady next door. She thought it was a snake so she hit it with a rake and now it’s only three foot four.

  • DancingCheese
    DancingCheese 4 days ago

    _Detected CANCER_
    _Kill it with _*_FIRE_*

  • Hope Davis
    Hope Davis 4 days ago


  • Mohammed Futa
    Mohammed Futa 4 days ago

    love the goku reference

  • MrSquashable
    MrSquashable 4 days ago

    Can we get an update vid on this plz

  • The YOLO Guy 334
    The YOLO Guy 334 5 days ago

    and in few years........

    t-series still cant beat pewdiepie

    • The YOLO Guy 334
      The YOLO Guy 334 5 days ago

      also the ugandand knukles will be revived after few more years

  • Alex Bloke
    Alex Bloke 5 days ago

    I hate this I really hope I die before this shit happens

  • Kenny Hong
    Kenny Hong 5 days ago

    Sad thing about living for a long time, the people who were able to watch this video before 2018 won't survive until then, o well, let's not be SOOOOO dark

  • robert sanchez
    robert sanchez 5 days ago

    this will give rise to the Pangea of human sloth and suffering ooo

  • halafradrimx
    halafradrimx 5 days ago

    Do any of you really want to allow humanity to become undefined through this?
    I guarantee conflict coming out of this.

  • Theo Gaming
    Theo Gaming 5 days ago

    love your liitle adventure time
    easter eggs maybe collab ( 0:25 )